Effects of Pueraria mirifica on reproduction, osteoporosis and neurodegeneration
Population genetics, ecology, morphology, behavior and physiology of non-human primates in Southeast Asia
 
Physiology
Primatology
 
Department of Biology, Faculty of Science
Chulalongkorn University
Phayathai Road, Pathumwan
Bangkok 10330, Thailand
office

Tel: 02-2185275
Fax: 02-2185275

e-mail
suchinda.m@chula.ac.th
synopsis

There are two approaches of my research; reproductive physiology and field study of non-human primates. For the first one, our focus is now about the effects of phytoestrogens from endemic Thai plant Pueraria mirifica on reproductive organs, bone (osteoporosis) and brain (Alzheimer’s disease) tested in vitro and in laboratory animals (rodents and monkeys).

For the second one, we research on distribution, morphology, ecology, genetics, behavior and physiology of macaque monkeys (Macaca spp.) in Southeast Asian countries, and some other Asian countries such as China and India. We also first discovered the macaque tool users at Laemson National Park, Thailand and in the vicinity of Andaman seacoast and Mergui Archipelago. Based on the vast knowledge on non-human primates gained both from the laboratory and field study, I am now establishing the National Primate Research Center of Thailand.

 
Director, National Primate Research Center of Thailand
Primate Research Unit
National Primate Research Center of Thailand (NPRCT)
 
1983-1987
B.Sc. (Biology) (2nd Class Honor)
Khon Kaen University, Khon Kaen, Thailand
1988-1990
M.Sc. (Zoology)
Chulalongkorn University, Bangkok, Thailand
1990-1994
Ph.D. (Biological Science - Reproductive Physiology)
Chulalongkorn University, Bangkok, Thailand
1996-1997
Post-doctoral training
Tsukuba Primate Center for Medical Science, (STA Fellowship Awardee) National Institutes of Health, Tsukuba, Japan
 
รางวัลศิษย์เก่าดีเด่นมหาวิทยาลัยขอนแก่นประจำปี 2557 (1 ธันวาคม 2557 สมาคมศิษย์เก่ามหาวิทยาลัยขอนแก่น)
รางวัลนักวิจยรุ่นเยาว์กองทุนศาสตราจารย์ คณะวิทยาศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย ประจาปี 2543
รางวัลเมธีวิจัย สกว. ปี 2544 และ 2548
รางวัลนักวิจยรุ่นเยาว์ดีเด่น คณะวิทยาศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย ประจำปี 2548
รางวัลผลงานวิจยดีมาก จุฬาลงกรณ์มหาวิทยาลัย ประจำปี 2550 เรื่อง ผลของพืชสมุนไพรกวาวเครือขาวต่อระบบสืบพันธุ์ มะเร็งเต้านม และกระดูก ในหนูและลิง (28 มีนาคม 2551)
The best poster award, presented in the Asian-Hope 2010 IPS Pre-congress Symposium and
Workshop at Inuyama, Japan (September 6-10, 2010).
รางวัลจุลมงกุฎ รางวัลนักวิจัยที่มีผลงานที่ได้รับการอ้างอิงสูงสุด ประจาปี 2553 กองทุนเพื่อการวิจัยของคณะวิทยาศาสตร์ (28 มกราคม 2554)
รางวัลจุลมงกุฎ รางวัลยกย่องเชิดชูเกียรติอาจารย์ด้านการเรียนการสอน ประจำปี 2554 ของคณะวิทยาศาสตร์ (28 มกราคม 2555)
รางวัลยกย่องเชิดชูเกียรติอาจารย์ด้านการเรียนการสอน กองทุนกาญจนาภิเษกเฉลิมพระเกียรติ ประจำปี 2554 ของจุฬาลงกรณ์มหาวิทยาลัย (22 มีนาคม 2555)
 
 
List of publications (from 2013 onwards):
  1. De la O-Rodríguez CE, Mevis L, Richter C, Malaivijitnond S, Ostner J, Schülke O. 2013. Reconciliation in Male Stump-tailed Macaques (Macaca arctoides): Intolerant males care for their social relationships. Ethology.119: 39-51.
  2. Matsudaira K, Reichard UH, Malaivijitnond S, Ishida T. 2013.Molecular evidence for the introgression between Hylobates lar and H. pileatus in the wild. Primates. 54: 33-37.
  3. Anukulthanakorn K, Malaivijitnond S, Kitahashi T, Jareonporn S, Parhar IS. 2013. Molecular events during the induction of neurodegeneration and memory loss in estrogen-deficient rats. General and Comparative Endocrinology. 181:316-323.
  4. Gumert MD, Hamada Y, Malaivijitnond S. 2013. Human activity negatively affects wild stone tool-using Burmese long-tailed macaques Macaca fascicularis aurea in Laeson National park, Thailand. Oryx-The International Journal of Conservation. Oct. 47:535-543.
  5. Gumert MD, Malaivijitnond S. 2013. Long-tailed macaques select mass of stone tools according to food type. Philosophical Transactions of the Royal Society– Series B (Biological Science). 368(1630):20120413 October.
  6. Haslam M, Gumert M, Biro D, Carvalho S, Malaivijitnond S. 2013. Use-wear patterns on wild macaque stone tools reveal their behavioural history. PLOS ONE. Aug 16;8(8):e72872.
  7. Barelli C, Matsudaira K, Wolf T, Roos C, Heistermann M, Hodges K, Ishida T, Malaivijitnond S, Reichard UH. 2013. Extra-pair paternity confirmed in wild white-handed gibbons. American Journal of Primatology. Dec;75(12):1185-1195
  8. Anukulthanakorn K, Jareonporn S, Malaivijitnond S. 2014. A simple, sensitive and reliable in vivo assay to evaluate the estrogenic activity of endocrine disruptors. Reproductive Medicine and Biology. 13:37-45.
  9. Sukmak M, Malaivijitnond S, Schülke O, Ostner J, Hamada Y, Wajjwalku W. 2014. Preliminary study of genetic diversity of Assamese macaque (Macaca assamensis) in Thailand based on mitochondrial DNA and microsatellite markers. Primates. 55:189-197.
  10. Asensio N, Brockelman WY, Malaivijitnond S, Reichard UH. 2014. White-handed gibbon (Hylobates lar) core area use over a short-time scale. Biotropica. 46 (4): 461—469..
  11. Jaroenporn S, Urasopon N, Watanabe G, Malaivijitnond S. 2014. Improvements of vaginal atrophy without systemic side effects after topical application of Pueraria mirifica, a phytoestrogen-rich herb, in postmenopausal cynomolgus macaques. Journal of Reproduction and Development. 60(3):238-245.
  12. Saisavoey T, Palaga T, Malaivijitnond S, Jaroenporn S, Thongchul N, Karnchanatat A, Sangvanich P. 2014. Anti-osteoclastogenic, estrogenic and antioxidant activities of cell suspension culture and tuber roots extract from Pueraria mirifica. Food Science and Biotechnology. 23(4):1253-1259.
  13. Tiyasatkulkovit W, Malaivijitnond S, Charoenphandhu N, Havill LM, Ford AL, VandeBerg JL. 2014. Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type I collagen in primary baboon osteoblasts. Phytomedicine. 21: 1498-1503.
  14. Jadejaroen J, Hamada Y, Kawamoto Y, Malaivijitnond S. 2014. Use of photogrammetry as a means to assess the hybrid between rhesus (Macaca mulatta) and long-tailed macaques (M. fascicularis). Primates. (IF2013 = 1.292). In press. (DOI) 10.1007/s10329-014-0450-2
 
 
Undergraduate Student
  1. นาย อานนท์ เปลี่ยนใจสุข
  2. นางสาวดิษยา ศรีนุติยากร
Graduate Student
  1. นางจรรยา เจตเจริญ (สัตววิทยา)
  2. นางสาวดลพร กิตติวนิชย์กุล (สัตววิทยา)
  3. นางสาวศรีจันทร์ บัลลังทรัพทย์ (สัตววิทยา)
  4. นายธราธร ฝายนันทะ (วิทยาศาสตร์ชีวภาพ)
  5. Mr. Florian Trebouet (Anthropology, Southern Illinois University of Carbondale)
  6. นายภานุพันธุ์ จินาวรณ์ (สัตววิทยา)
  7. นางสาวฤดีมาศ ยุบลพันธุ์ (สัตววิทยา)
  8. นางสาวสโรชา สุทนต์ (สัตววิทยา)
  9. นางสาวนลินา เอี่ยมพิชิตกิจการ (สัตววิทยา)
Post-doctoral Student

Dr. Kazunari Matsudaira

 
from 2008 onward
  1. Malaivijitnond S, Sae-low W, Hamada Y. 2008. The Human-ABO blood groups of free-ranging long- tailed macaques (Macaca fascicularis) and parapatric rhesus macaques (M. mulatta) in Thailand. Journal of Medical Primatology. 37:31-37.
  2. Malaivijitnond S, Hamada Y. 2008 Current situation and status of long-tailed macaques (Macaca fascicularis) in Thailand Nat Hist J of Chulalongkorn Univ. 8: 185-204.
  3. Urasopon N, Hamada Y, Asaoka K, Poungmali U, Malaivijitnond S. 2008. Isoflavone contents in rodent diets and its estrogenic effect on vaginal cornification in Pueraria mirifica-treated rats. Science Asia. 34: 371-376.
  4. Föger F, Malaivijitnond S, Wannaprasert T, Huck C, Bernkop-Schnürch A, Werle M. 2008. Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats. Journal of Drug Targeting.
    16(2): 149-155.
  5. Taepongsorat L, Tangpraprutgul P, Kitana N, Malaivijitnond S. 2008. Stimulating effects of quecertin on sperm quality and reproductive organs in adult male rats. Asian Journal of Andrology. 10 (2)
    March: 249-258.
  6. Urasopon N, Hamada Y, Cherdshewasart W, Malaivijitnond S. 2008. Preventive effects of Pueraria mirifica on bone loss in ovariectomized rats. Maturitas. 59(2):137-148 (IF 2008= 2.032)
  7. Seethamchai S, Putaporntip C, Malaivijitnond S, Cui L, Jongwutiwes S. 2008. Malaria and Hepatocystis spp. In wild macaques, southern Thailand. American Journal of Tropical Medicine and Hygiene. 78 (4): 646-653.
  8. Koyabu DB, Malaivijitnond S, Hamada Y. 2008. Pelage color variation of Macaca arctoides and its evolutionary implications.International Journal of Primatology. 29: 531-541.
  9. Masaharu Takahashi, Nobuo Masataka, Suchinda Malaivijitnond, Siriwat Wongsiri. 2008. Future rice is discounted less steeply than future money in Thailand. The Psychological Record. 58 (2): 175-190.
  10. Cherdshewasart W, Bhuntaku P, Panriansaen R, Dahlan W, Malaivijitnond S. 2008. Androgen disruption and toxicity tests of Butea superba Roxb., a traditional herb used for treatment of erectile dysfunction, in male rats Maturitas. 60: 131-137.
  11. Hamada Y, Suryobroto B, Goto S, Malaivijitnond S. 2008. Morphological and body color variation in Thai Macaca fascicularis fascicularis north and south of the Isthmus of Kra. International Journal of Primatology. 29: 1271-1294.
  12. Trisomboon H, Watanabe G, Taya K, Malaivijitnond S. 2008. Oral administration of Kaempferia parviflora did not disturb male reproduction in rats. Journal of Reproduction and Development. 54: 375-380.
  13. Cherdshewasart W, Sriwatcharakul S, Malaivijitnond S. 2008. Variance of estrogenic activity of the phytoestrogen-rich plant.Maturitas. 61: 350-357.
  14. Malaivijitnond S, Ketsuwan A, Watanabe G, Taya K, Cherdshewasart W. 2009. Androgenic activity of the Thai traditional male potency herb, Butea superba Roxb., in female rats. Journal of Ethnopharmacology. 121(1):123-129.
  15. Gumert MD, Kluck M, Malaivijitnond S. 2009. The physical characteristics and usage patterns of stone axe and pounding hammers used by long-tailed macaques in the Andaman sea region of Thailand. American Journal of Primatology. 71 (7): 594-608.
  16. Richter C, Mevis L, Malaivijitnond S, Schulke O, Ostner J. 2009. Social relationships in free-ranging male Macaca arctoides.International Journal of Primatology. 30:625-642.
  17. Maruhashi T, Nilpaung W, Malaivijitnond S. 2009. A preliminary report on socio-ecological study of Macaca arctoides in Khao Krapuk Khao Taomo non-hunting area, Thailand. The Journal of Human and Cultural Sciences. 11 (3): 11-29.
  18. Son VD, Malaivijitnond S, Gotoh S, Tri CQ, Hung NV, Hoang LV, Trang TC, Hamada Y. 2009.
    Report on present distribution and status of macaques in Vietnam. Laboratory Primate Newsletter. 48 (1): 10-14.
  19. Malaivijitnond S, Tungmunnithum D, Gittarasanee S, Kawin K, Limjunyawong N. 2010. Puerarin exhibits weak estrogenic activity in female rats. Fitoterapia. 81: 569-576.
  20. Malaivijitnond S, Ketsuwan A, Watanabe G, Taya K, Cherdshewasart W. 2010. Luteinizing hormone reduction by the male potency herb, Butea superba Roxb. Brazilian Journal of Medical and Biological Research. 43(9):843-852.
  21. Asensio N, Brockelman WY, Malaivijitnond S, Reichard UH. 2011. Gibbon travel paths are goal- oriented. Animal Cognition. 14:395-405.
  22. Gumert MD, Hoong LK, Malaivijitnond S. 2011. Sex differences in the stone tool-use behavior of a natural population of long-tailed macaque (Macaca fascicularis aurea). American Journal of Primatology. 73:1239-1249.
  23. Hiwatashi T, Mikami A, Katsumura T, Suryobroto B, Perwitasari-Farajallah D, Malaivijitnond S, Siriaroonrat B, Ota H, Goto S, Kawamura S. 2011. Gene conversion and purifying selection shape nucleotide variation in gibbon L/M opsin genes. BMC Evolutionary Biology. 11:312-325.
  24. Malaivijitnond S. 2012. Medical applications of phytoestrogens from Pueraria mirifica Thai herb. Frontiers of Medicine. 6(1):8-21.
  25. Gomuttapong S, Pewphong R, Choeisiri S, Jaroenporn S, Malaivijitnond S. 2012. Testing of the estrogenic activity and toxicity of Stephania venosa in ovariectomized rats. Toxicology Mechanisms and Methods. 22(6): 445-457.
  26. Malaivijitnond S, Arsaithamkul V, Tanaka H, Pomchote P, Jaroenporn S, Suryobroto B, Hamada Y.
    2012. Boundary zone between northern and southern pig-tailed macaques and their morphological differences. Primates. 53:377-389.
  27. Tiyasatkulkovit W, Charoenphandhu N, Wongdee K, Thongbunchoo J, Krishnamra N, Malaivijitnond S. 2012. Upregulation of osteoblastic differentiation marker mRNA expression in osteoblast-like UMR 106 cells by puerarin and phytoestrogens from Pueraria mirificaPhytomedicine. 19(13):1147-1155.
  28. Gumert MD, Malaivijitnond S. 2012. Marine prey processed with stone tools by Burmese longtailed macaques (Macaca fascicularis aurea) in intertidal habitats. American Journal of Physical Anthropology.
    149(3):447-457.
  29. De la O-Rodríguez CE, Mevis L, Richter C, Malaivijitnond S, Ostner J, Schülke O. 2013.
    Reconciliation in Male Stump-tailed Macaques (Macaca arctoides): Intolerant males care for their social relationships.Ethology.119: 39-51.
  30. Matsudaira K, Reichard UH, Malaivijitnond S, Ishida T. 2013.Molecular evidence for the introgression between Hylobates lar and H. pileatus in the wild. Primates. 54: 33-37.
  31. Anukulthanakorn K, Malaivijitnond S, Kitahashi T, Jareonporn S, Parhar IS. 2013. Molecular events during the induction of neurodegeneration and memory loss in estrogen-deficient rats. General and Comparative Endocrinology. 181:316-323.
  32. Gumert MD, Hamada Y, Malaivijitnond S. 2013. Human activity negatively affects wild stone tool- using Burmese long-tailed macaques Macaca fascicularis aurea in Laeson National park, Thailand. Oryx-The International Journal of Conservation. (In press).
  33. Anukulthanakorn K, Jareonporn S, Malaivijitnond S. 2013. A simple, sensitive and reliable in vivo assay to evaluate the estrogenic activity of endocrine disruptors. Reproductive Medicine and Biology. (in press).
  34. Barelli C, Matsudaira K, Wolf T, Roos C, Heistermann M, Hodges K, Ishida T, Malaivijitnond S, Reichard UH. 2013. Genetic mating system of wild white gibbons (Hylobates lar) in pair-living and multi-male group. American Journal of Primatology. (In press)
  35. Haslam M, Gumert M, Biro D, Carvalho S, Malaivijitnond S. 2013. Use-wear patterns on wild macaque stone tools reveal their behavioural history. PLOS ONE. (In press).
  36. Gumert MD, Malaivijitnond S. 2013. A field experiment and natural observations of weight selection in stone tool-using Burmese long-tailed macaques (Macaca fascicularis aurea). Philosophical Transactions of the Royal Society– Series B (Biological Science).